Stents and Medical Devices

Key Paper Overviews:

A computational test-bed to assess coronary stent implantation mechanics using a population-specific approach

clare conwayIn-stent restenosis (ISR) is hypothesized to occur for reasons that include injury to the vessel wall caused by stent placement. This research aims to facilitate more comprehensive evaluation of stents in the design phase, by generating more realistic arterial environments and corresponding stress states than have been considered heretofore. A systematic geometric test-bed with varying levels of arterial curvature and stenosis severity is developed and used to evaluate the implantation behaviour of two stent designs using finite element analysis. Results are analysed using tissue damage estimates and lumen gain comparisons for each design. Results indicate that stent design does not have a major impact on lumen gain behaviour but may have an influence on the potential for tissue damage. The level of stenosis in the arterial segments is seen to have a strong impact on the results while the effects of arterial curvature appear to be design dependent. Link to paper